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Phase III - Stealth Is.

“In the quietude, you may find solace in knowing.” “In knowing, you will find the solace of quietude.”

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Category: alchemy

A new “tea bag” uses nano-fibers to suck contaminants and bacteria out of water, providing a desperately-needed, cheap solution for the billions of people without clean drinking water.Researchers at South Africa’s Stellenbosch University made the device from the same material used for the bags of the country’s popular rooibos tea. Inside the sachets are two tiny destroyers of all things unsafe: ultra-thin nanoscale fibers, which filter harmful contaminants, and bacteria-killing grains of carbon.

To use the device, a person simply has to place the bag in the neck of a water bottle, and the bag cleans the water as he or she drinks. A single bag can filter up to a liter of even the most heavily polluted water. The bags are thrown away once used.

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By analyzing just 150 spots on the genome, researchers can predict who will live to extreme old age with almost 80 percent accuracy, according to a study published online today in the journal Science. Researchers from Boston University employed a widely used genetic-screening technology to find genetic variations that occur more frequently in centenarians–people age 100 and older.
In addition to providing a potential way to predict who might live into their 100s, the findings suggest that genetics play a major role in surviving to extreme old age. And the team hopes that identifying the genes and corresponding molecular mechanisms that promote longevity will give new insight into how to prevent or delay age-related diseases, such as heart disease, Alzheimer’s, and cancer.

“Centenarians are a model of aging well,” says Thomas Perls, director of the New England Centenarian Study at Boston Medical Center and an author of the study. Previous findings from the project, the largest study of centenarians in the world, show that 90 percent of them are free of disability to an average age of 93. “They seem to compress disability to the end of their lives,” says Perls. “I am very hopeful that understanding how centenarians do that will lead to new strategies for therapies.”

Perhaps most surprisingly, preliminary analysis showed that centenarians had just as many genetic variants linked to diseases as did people in the control group. “That suggests that what makes people live long lives is not lack of genetic disposition to disease but longevity-promoting genes,” says Paola Sebastiani, a biostatistician at Boston University and coauthor of the study. “If longevity variants cancel out disease-associated variants, it could open new ways of treating age-related diseases.”

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Most scientists have viewed electrical fields within the brain as the simple byproducts of neuronal activity. However, Yale scientists report in the July 15 issue of the journal Neuron that electrical fields can also influence the activity of brain cells.

The finding helps explain why techniques that influence electrical fields such as transcranial magnetic stimulation and deep brain stimulation are effective for the treatment of various neurological disorders, including depression. The study also “raises many questions about the possible effects of electrical fields, such as power lines and cell phones, in which we immerse ourselves,” said David McCormick, the Dorys McConnell Duberg Professor of Neurobiology at Yale School of Medicine, a researcher of the Kavli Institute of Neuroscience and senior author of the study.

The chemical process that triggers tiny charges in the membranes of neurons causes much of the brain’s electrical activity. Electroencephalograms, or EEGs, detect these fluctuations when they occur in large numbers of neurons together. These internal electrical signals contain information about certain cognitive and behavioral states but, until now, it had not been shown whether they actually change the activity of the brain itself.

McCormick and Flavio Frohlich, a postdoctoral research associate, introduced slow oscillation signals into brain tissue and found that the signal created a sort of feedback loop, with changes in electrical field guiding neural activity, which in turn strengthened the electrical field.

“It’s like asking whether the roar of the crowd in the football stadium also influences you to cheer as well. And in turn, your cheering encourages others to cheer along with you.” McCormick said.

The ability of electric fields generated by the brain to influence its own activity appears to be particularly prominent during epileptic seizures. However, the influence of electric fields is not limited to these pathological states. The study of Frohlich and McCormick demonstrates that the electrical fields also influence brain function during normal activities such as sleep.

See also: Effects of 6-10 Hz ELF on Brain Waves

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Take frozen cells from a dead animal, reprogram them to become sperm and eggs, then use these to bring endangered species back from the brink.

That’s the aim of a collaboration between the San Diego zoo and The Scripps Research Institute in La Jolla, California. At the annual meeting of the International Society for Stem Cell Research in San Francisco last week, Inbar Friedrich Ben-Nun and Jeanne Loring of Scripps described how they have created induced pluripotent stem (iPS) cells from the frozen skin cells of a deceased male drill (Mandrillus leucophaeus), an endangered monkey found in Nigeria, Cameroon and Equatorial Guinea.

The team’s long-term goal is to coax iPS cells into becoming sperm and eggs. They will be making iPS cells from tissue held by San Diego zoo’s Frozen Zoo project - which has samples from some 8400 individuals representing more than 800 species. The sperm and eggs could be used in IVF treatments to add genetic diversity to captive breeding programmes. “You could actually breed from animals that are dead,” says Loring.

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If the human species should be destroyed on Earth, our future may reside on the Moon if plans.being drawn up for a “Doomsday ark” on the moon by the European Space Agency are carried through. The Ark will contain the essentials of life and human civilization, to be activated in the event of earth being devastated by a giant asteroid or nuclear war.

The construction of a lunar information bank, discussed at a conference in Strasbourg last month, would provide survivors on Earth with a remote-access toolkit to rebuild the human race.

A basic version of the ark would contain hard discs holding information such as DNA sequences and instructions for metal smelting or planting crops. It would be buried in a vault just under the lunar surface and transmitters would send the data to heavily protected receivers on earth. if no receivers survived, the ark would continue transmitting the information until new ones could be built.

The vault could later be extended to include natural material including microbes, animal embryos and plant seeds and even cultural relics such as surplus items from museum stores.

As a first step to discovering whether living organisms could survive, European Space Agency scientists are hoping to experiment with growing tulips on the moon within the next decade.

Thanks to John Harrigan of Foolish People for pointing this interesting article out.

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Previous experiments led by Graham Fleming, a physical chemist holding joint appointments with Berkeley Lab and UC Berkeley, pointed to quantum mechanical effects as the key to the ability of green plants, through photosynthesis, to almost instantaneously transfer solar energy from molecules in light harvesting complexes to molecules in electrochemical reaction centers. Now a new collaborative team that includes Fleming have identified entanglement as a natural feature of these quantum effects. When two quantum-sized particles, for example a pair of electrons, are “entangled,” any change to one will be instantly reflected in the other, no matter how far apart they might be. Though physically separated, the two particles act as a single entity.

“This is the first study to show that entanglement, perhaps the most distinctive property of quantum mechanical systems, is present across an entire light harvesting complex,” says Mohan Sarovar, a post-doctoral researcher under UC Berkeley chemistry professor Birgitta Whaley at the Berkeley Center for Quantum Information and Computation. “While there have been prior investigations of entanglement in toy systems that were motivated by biology, this is the first instance in which entanglement has been examined and quantified in a real biological system.”

The results of this study hold implications not only for the development of artificial photosynthesis systems as a renewable non-polluting source of electrical energy, but also for the future development of quantum-based technologies in areas such as computing – a quantum computer could perform certain operations thousands of times faster than any conventional computer.

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A novel transistor controlled by the chemical that provides the energy for our cells’ metabolism could be a big step towards making prosthetic devices that can be wired directly into the nervous system.

Transistors are the fundamental building blocks of electronic gadgets, so finding ways to control them with biological signals could provide a route towards integrating electronics with the body.

Aleksandr Noy at the Lawrence Livermore National Laboratory in California and colleagues chose to control their transistor with adenosine triphosphate (ATP) – the molecular fuel found in nearly all living cells.

The new transistor is made up of a carbon nanotube, which behaves as a semiconductor, bridging the gap between two metal electrodes and coated with an insulating polymer layer that leaves the middle section of the nanotube exposed. The entire device is then coated again, this time with a lipid bi-layer similar to those that form the membranes surrounding our body’s cells.

Noy claims that this is the first example of a truly integrated bioelectronic system. “I hope that this type of technology could be used to construct seamless bioelectronic interfaces to allow better communication between living organisms and machines.”

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A variety of studies by numerous investigators are demonstrating that gold nanoparticles have real promise as anticancer agents. When irradiated with light, gold nanoparticles become hot quickly, hot enough to generate explosive microbubbles that will kill nearby cancer cells, a physical process known as the photothermal effect.

To boost this approach, researchers at the University of California, Los Angeles, have developed a method for creating supramolecular assemblies of gold nanoparticles that function as highly efficient photothermal agents of a size designed to optimize their delivery to tumors.

Hsien-Rong Tseng and his colleagues reported their work in the journal Angewandte Chemie International Edition. Dr. Tseng is a member of the Nanosystems Biology Cancer Center, a National Cancer Institute Center for Cancer Nanotechnology Excellence.

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All those paper transistors and paper displays that scientists have been designing can now be powered by an onboard power source, thanks to the development of a new paper supercapacitor. Designed by researchers at Stanford University, the paper supercapacitor is made by simply printing carbon nanotubes onto a treated piece of paper. The researchers hope that the integrated design could lead to the development of low-cost, disposable paper electronics.

In the paper supercapacitor, all the necessary components are integrated onto a single sheet of paper in the form of single walled carbon nanotubes (SWNTs). High-speed printing could be used to print the SWNTs directly onto a piece of paper - anything from Xerox paper to newspaper and even grocery ads will work.

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Scientists are taking a new look at hallucinogens, which became taboo among regulators after enthusiasts like Timothy Leary promoted them in the 1960s with the slogan “Turn on, tune in, drop out.” Now, using rigorous protocols and safeguards, scientists have won permission to study once again the drugs’ potential for treating mental problems and illuminating the nature of consciousness.

After taking the hallucinogen, Dr. Martin put on an eye mask and headphones, and lay on a couch listening to classical music as he contemplated the universe.

“All of a sudden, everything familiar started evaporating,” he recalled. “Imagine you fall off a boat out in the open ocean, and you turn around, and the boat is gone. And then the water’s gone. And then you’re gone.”

Today, more than a year later, Dr. Martin credits that six-hour experience with helping him overcome his depression and profoundly transforming his relationships with his daughter and friends. He ranks it among the most meaningful events of his life, which makes him a fairly typical member of a growing club of experimental subjects.

Researchers from around the world are gathering this week in San Jose, Calif., for the largest conference on psychedelic science held in the United States in four decades. They plan to discuss studies of psilocybin and other psychedelics for treating depression in cancer patients, obsessive-compulsive disorder, end-of-life anxiety, post-traumatic stress disorder and addiction to drugs or alcohol.

Scientists are especially intrigued by the similarities between hallucinogenic experiences and the life-changing revelations reported throughout history by religious mystics and those who meditate. These similarities have been identified in neural imaging studies conducted by Swiss researchers and in experiments led by Roland Griffiths, a professor of behavioral biology at Johns Hopkins.

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Read more on the topic and other exo-skeletons reaching the market.

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Stanford scientists have plugged into algae cells and harnessed a tiny electrical current. They found it at the very source of energy production – photosynthesis, a plant’s method of converting sunlight to chemical energy. It may be a first step toward generating high-efficiency bioelectricity that doesn’t give off carbon dioxide as a byproduct, the researchers say.

“We believe we are the first to extract electrons out of living plant cells,” said WonHyoung Ryu, the lead author of the paper published in the March issue of Nano Letters. Ryu conducted the experiments while he was a research associate for mechanical engineering Professor Fritz Prinz.

The Stanford research team developed a unique, ultra-sharp nanoelectrode made of gold, specially designed for probing inside cells. They gently pushed it through the algal cell membranes, which sealed around it, and the cell stayed alive. From the photosynthesizing cells, the electrode collected electrons that had been energized by light and the researchers generated a tiny electrical current.

In this experiment, the researchers intercepted the electrons just after they had been excited by light and were at their highest energy levels. They placed the gold electrodes in the chloroplasts of algae cells and siphoned off the electrons to generate the tiny electrical current.

The result, the researchers say, is electricity production that doesn’t release carbon into the atmosphere. The only byproducts of photosynthesis are protons and oxygen.

“This is potentially one of the cleanest energy sources for energy generation,” Ryu said. “But the question is, is it economically feasible?”

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Organovo will distribute its $200,000 inkjet-like organ printers to medical research centers starting this year. Their “ink” comes from stem cells (from adult bone marrow) guided by growth factors into specific cell types, then packed into droplets of “ink” containing up to 30,000 cells to be printed onto sheets of organic biopaper where they self-assemble into functional tissue.

Though at first they’ll only print “very basic tissues like blood vessels”, the CSO of Organovo sees the business potential in using their bio-printers to create artificial human organs for implanting.

Bioprinters may one day be capable of printing tissues and organs not just for use by surgeons, but directly into the body. Dr. Atala is currently working on the design for a bioprinter that would scan the contours of a body part requiring a skin graft and then print skin onto it. As for bigger body parts, Organovo’s Dr. Forgacs thinks they may ultimately come in different shapes and sizes — designer organs. What this might mean to the sex industry… well, let’s not go there. Organovo is definitely a company to keep an eye on.

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Transplanting fetal neurons into the brains of young mice opens a new window on neural plasticity, or flexibility in the brain’s neural circuits. The research, published today in the journal Science, suggests that the brain’s ability to radically adapt to new situations might not be permanently lost in youth, and helps to pinpoint the factors needed to reintroduce this plasticity.

A better understanding of brain plasticity could one day point to new ways to treat brain injury and other neurological problems by returning the brain to a younger, more malleable state.

Scientists aren’t yet sure how the cells induce this second period of malleability. Stryker’s team and others had previously shown that the cells’ inhibitory signaling plays a key role–the critical period can be delayed or induced earlier by mimicking the inhibitory effects of the cells with drugs, such as valium. But in these previous experiments, it was not possible to induce a second critical period after the normal one. “Once you’ve had it, can never get another one, at least until these transplant experiments,”

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